The 2012 edition of Florens is coming up soon - this is a biannual cultural event which will be focusing this year on the theme: "From the Grand Tour to the Global Tour". It is a week long of conferences, lectures, events, round tables and more focussing on culture and the role it plays in society. There is a schedule of events on their website (Italian only still).
Two years ago when one of the main exhibits of the conference was to sod Piazza Duomo:
I am also scheduled to be attending and blogging about the events and conferences as part of the "team" - I will keep you posted